New patent for the synthesis of cyclohexylcarboxylic acid from benzoic acid

A groundbreaking method for synthesizing cyclohexylcarboxylic acid has recently been granted a national invention patent by the Changchun Institute of Applied Chemistry, part of the Chinese Academy of Sciences. This innovative approach involves the hydrogenation of benzoic acid using a supported transition metal ruthenium catalyst in the presence of supercritical carbon dioxide and cyclohexyl formic acid. The reaction takes place under controlled conditions where hydrogen facilitates a ring-catalyzed transformation. After the reaction is complete, the product is extracted using supercritical carbon dioxide, which serves as an efficient and environmentally friendly solvent. The catalyst is then easily separated from the final mixture, allowing for potential reuse and reducing overall waste. This process stands out for its mild reaction conditions, minimal use of organic solvents, high yield, and excellent product quality. It represents a significant advancement in green chemistry and sustainable synthesis methods, offering a cleaner and more efficient alternative to traditional approaches. The technology not only enhances industrial production efficiency but also aligns with global efforts to reduce environmental impact through eco-friendly chemical processes.

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